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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
22.12
Human Site:
Y410
Identified Species:
40.56
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
Y410
G
P
N
G
E
F
A
Y
L
Y
S
Q
C
Y
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
Y475
G
P
N
G
E
F
A
Y
L
Y
S
Q
C
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
Y403
G
P
S
G
E
F
A
Y
L
Y
S
Q
C
Y
E
Rat
Rattus norvegicus
NP_001100276
525
59200
Y407
G
P
S
G
E
F
A
Y
L
Y
S
Q
C
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
Y451
G
P
S
G
E
F
A
Y
L
Y
N
Q
C
Y
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
E395
L
D
F
G
P
S
G
E
F
S
Y
L
Y
G
E
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
Y411
G
P
N
A
E
F
T
Y
L
Y
S
Q
C
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
A430
Y
G
L
T
E
E
W
A
V
H
D
G
Q
C
Y
Honey Bee
Apis mellifera
XP_625125
493
56012
E375
R
D
F
G
V
E
H
E
F
A
P
L
D
G
E
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
A390
S
D
Y
G
E
D
S
A
W
A
A
L
K
D
K
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
A404
G
P
D
Q
A
F
Q
A
L
Q
G
Q
C
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
N475
K
L
K
H
D
F
G
N
D
K
E
F
Y
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
N585
R
F
K
T
S
G
F
N
V
D
L
N
M
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
13.3
86.6
N.A.
6.6
13.3
13.3
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
N.A.
13.3
86.6
N.A.
20
13.3
33.3
60
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
39
24
0
16
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
54
8
0
% C
% Asp:
0
24
8
0
8
8
0
0
8
8
8
0
8
8
0
% D
% Glu:
0
0
0
0
62
16
0
16
0
0
8
0
0
8
70
% E
% Phe:
0
8
16
0
0
62
8
0
16
0
0
8
0
0
8
% F
% Gly:
54
8
0
62
0
8
16
0
0
0
8
8
0
16
0
% G
% His:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
16
0
0
0
0
0
0
8
0
0
8
0
16
% K
% Leu:
8
8
8
0
0
0
0
0
54
0
8
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
24
0
0
0
0
16
0
0
8
8
0
0
0
% N
% Pro:
0
54
0
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
8
0
54
8
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
24
0
8
8
8
0
0
8
39
0
0
8
0
% S
% Thr:
0
0
0
16
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
47
0
47
8
0
16
54
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _